The National Aeronautics and Space Administration (NASA), through the Astrophysics Division and its Cosmic Origins (COR) Program, is soliciting information through this Request for Information (RFI) pertaining to potential ultraviolet (UV) and visible wavelength astrophysics science investigations. Specifically, NASA seeks information that can be used to develop a cohesive set of science goals that motivate and support the development of the next generation of UV/Visible space astrophysics missions. Information may include broad science goals, justifications for investigations that support COR science goals (for examples, visit Cosmic Origins), specific measurements or proxy observing plans for well-defined astrophysical experiments, or any aspect of scientific inquiry in the UV/Visible that supports the above COR goals.